M. Garcia-Sancho,
M. García-Sancho
Biology, Computing, and the History of Molecular Sequencing
From Proteins to DNA, 1945-2000
Paperback Engels 2012 9781137543325
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.
Specificaties
ISBN13:9781137543325
Taal:Engels
Bindwijze:paperback
Uitgever:Palgrave Macmillan UK
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Inhoudsopgave
Introduction: An Historical Approach to Sequencing PART I: EMERGENCE: FREDERICK SANGER'S PIONEERING TECHNIQUES (1943-1977) The Sequence of Insulin and the Configuration of a New Biochemical Form of Work (1943-1962) From Chemical Degradation to Biological Replication (1962-1977) PART II: MECHANISATION – 1: COMPUTING AND THE AUTOMATION OF SEQUENCE RECONSTRUCTION (1962-1987) Sequencing Software and the Shift in the Practice of Computation Sequence Databases and the Emergence of 'Information Engineers' PART III: MECHANISATION – 2: THE SEQUENCER AND THE AUTOMATION OF SEQUENCE CONSTRUCTION (1980-2000) A New Approach to Sequencing at Caltech The Commercialisation of the DNA Sequencer Conclusions: A Long History of Practices Appendix 1: Oral Histories Appendix 2: Archival Sources Notes Bibliography
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